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Cellosaurus UKAi002-B-1 (CVCL_A7GX)

[Text version]
Cell line name UKAi002-B-1
Synonyms PV1 JAK2 V617F het:CXCL4 KO; JAK2 V617Fhet:CXCL4KO
Accession CVCL_A7GX
Resource Identification Initiative To cite this cell line use: UKAi002-B-1 (RRID:CVCL_A7GX)
Comments From: Universitatsklinikum Aachen; Aachen; Germany.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:8861; PF4.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Disease Polycythemia vera (NCIt: C3336)
Polycythemia vera (ORDO: Orphanet_729)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A7GV (UKAi002-B)
Sex of cell Female
Age at sampling 45Y
Category Induced pluripotent stem cell
STR profile Source(s): PubMed=34391098

Markers:
AmelogeninX
CSF1PO12
D2S133817,25
D3S135815,16
D5S81811,13
D7S8208,9
D8S117912,15
D13S31712,13
D16S53911,14
D18S5116
D19S43313,14
D21S1129,30.2
FGA24
TH019,9.3
TPOX8,10
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=34391098; DOI=10.1016/j.scr.2021.102490
Boehnke J., Atakhanov S., Szymanski de Toledo M.A., Schuler H.M., Sontag S., Chatain N., Koschmieder S., Brummendorf T.H., Kramann R., Zenke M.
CRISPR/Cas9 mediated CXCL4 knockout in human iPS cells of polycythemia vera patient with JAK2 V617F mutation.
Stem Cell Res. 55:102490-102490(2021)

Cross-references
Cell line databases/resources hPSCreg; UKAi002-B-1
Biological sample resources BioSamples; SAMEA8686795
Encyclopedic resources Wikidata; Q107117215
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number5