Cellosaurus logo
expasy logo

Cellosaurus GZHMCi007-A (CVCL_A7GC)

[Text version]
Cell line name GZHMCi007-A
Accession CVCL_A7GC
Resource Identification Initiative To cite this cell line use: GZHMCi007-A (RRID:CVCL_A7GC)
Comments From: The Third Affiliated Hospital of Guangzhou Medical College; Guangzhou; China.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:18078; ZBTB7A.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:4824; HBA2; Simple; p.Ter143Glnext*32 (c.427T>C); ClinVar=VCV000015624; Zygosity=Homozygous; Note=Hb Constant Spring (from parent cell line).
Disease Alpha thalassemia (NCIt: C34368)
Alpha-thalassemia (ORDO: Orphanet_846)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E4G8 (SU-iPS-1)
Sex of cell Male
Age at sampling 6M
Category Induced pluripotent stem cell
STR profile Source(s): PubMed=34403853

Markers:
AmelogeninX,Y
CSF1PO10,12
D1S165615,16
D2S133823
D3S135816,18
D5S81811,12
D6S104310,12
D7S82011,12
D8S117910,12
D12S39119,21
D13S3178,10
D16S53911
D18S5111,14
D19S43312,15.2
D21S1129,32.2
FGA24
Penta D9
Penta E10,15
TH019,9.3
TPOX11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=34403853; DOI=10.1016/j.scr.2021.102494
Chen D.-Y., Song B., Cheng Y., Zhu L.-F., Lu D., Liu N.-Q., Yang Y.-H., Sun X.-F.
Generation of a homozygous ZBTB7A knockout human induced pluripotent stem line by CRISPR/Cas9 editing.
Stem Cell Res. 55:102494-102494(2021)

Cross-references
Cell line databases/resources hPSCreg; GZHMCi007-A
Encyclopedic resources Wikidata; Q107115212
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number5