ID   PF130
AC   CVCL_A7EV
DR   Wikidata; Q107116657
RX   PubMed=33669371;
CC   Sequence variation: Mutation; HGNC; HGNC:6840; MAP2K1; Simple; p.Glu102_Lys104delinsGln (c.303_310del8ins); Zygosity=Unspecified (PubMed=33669371).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C165497; Spitz melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   37Y
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 19-12-24; Version: 5
//
RX   PubMed=33669371; DOI=10.3390/cancers13040829; PMCID=PMC7920251;
RA   Hegedus L., Okumus O., Livingstone E., Baranyi M., Kovacs I., Dome B.,
RA   Tovari J., Bankfalvi A., Schadendorf D., Aigner C., Hegedus B.;
RT   "Allosteric and ATP-competitive MEK-inhibition in a novel spitzoid
RT   melanoma model with a RAF- and phosphorylation-independent
RT   mutation.";
RL   Cancers (Basel) 13:829.1-829.12(2021).
//