ID   UT-SCC-126A
AC   CVCL_A7EC
SY   University of Turku-Squamous Cell Carcinoma-126A
DR   cancercelllines; CVCL_A7EC
DR   GEO; GSM2883398
DR   GEO; GSM2888861
DR   Wikidata; Q107117366
RX   PubMed=29970484;
RX   PubMed=30135316;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu130Phe (c.388C>T); ClinVar=VCV000216466; Zygosity=Heterozygous (PubMed=29970484).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu171Lys (c.511G>A); ClinVar=VCV000141566; Zygosity=Heterozygous (PubMed=29970484).
CC   Omics: Array-based CGH.
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Oral cavity, lower lip; UBERON=UBERON_0001835.
ST   Source(s): PubMed=30135316
ST   Amelogenin: X
ST   CSF1PO: 10,13
ST   D13S317: 9,12
ST   D16S539: 12,13
ST   D18S51: 13
ST   D19S433: 14,15
ST   D21S11: 28,30
ST   D2S1338: 19
ST   D3S1358: 16
ST   D5S818: 11,12
ST   D7S820: 10
ST   D8S1179: 13,14
ST   FGA: 22
ST   TH01: 8,9
ST   TPOX: 9,11
ST   vWA: 17,18
DI   NCIt; C4833; Oral cavity squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   81Y
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 19-12-24; Version: 6
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RX   PubMed=29970484; DOI=10.1158/1535-7163.MCT-17-0733;
RA   Lepikhova T., Karhemo P.-R., Louhimo R., Yadav B., Murumagi A.,
RA   Kulesskiy E., Kivento M., Sihto H., Grenman R., Syrjanen S.M.,
RA   Kallioniemi O.-P., Aittokallio T., Wennerberg K., Joensuu H., Monni O.;
RT   "Drug-sensitivity screening and genomic characterization of 45
RT   HPV-negative head and neck carcinoma cell lines for novel biomarkers
RT   of drug efficacy.";
RL   Mol. Cancer Ther. 17:2060-2071(2018).
//
RX   PubMed=30135316; DOI=10.1172/jci.insight.122204; PMCID=PMC6141174;
RA   Jamieson S.M.F., Tsai P., Kondratyev M.K., Budhani P., Liu A.,
RA   Senzer N.N., Chiorean E.G., Jalal S.I., Nemunaitis J.J., Kee D.,
RA   Shome A., Wong W.W., Li D., Poonawala-Lohani N., Kakadia P.M.,
RA   Knowlton N.S., Lynch C.R.H., Hong C.R., Lee T.W., Grenman R.,
RA   Caporiccio L., McKee T.D., Zaidi M., Butt S., Macann A.M.J.,
RA   McIvor N.P., Chaplin J.M., Hicks K.O., Bohlander S.K., Wouters B.G.,
RA   Hart C.P., Print C.G., Wilson W.R., Curran M.A., Hunter F.W.;
RT   "Evofosfamide for the treatment of human papillomavirus-negative head
RT   and neck squamous cell carcinoma.";
RL   JCI Insight 3:e122204.1-e122204.19(2018).
//