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Cellosaurus UT-SCC-110A (CVCL_A7EB)

[Text version]
Cell line name UT-SCC-110A
Synonyms University of Turku-Squamous Cell Carcinoma-110B
Accession CVCL_A7EB
Resource Identification Initiative To cite this cell line use: UT-SCC-110A (RRID:CVCL_A7EB)
Comments Omics: Array-based CGH.
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Nose, nasal cavity, maxillary sinus; UBERON=UBERON_0001764.
Sequence variations
Disease Maxillary sinus squamous cell carcinoma (NCIt: C6064)
Squamous cell carcinoma of the nasal cavity and paranasal sinuses (ORDO: Orphanet_500464)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A091 ! UT-SCC-110B
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
STR profile Source(s): PubMed=30135316

Markers:
AmelogeninX
CSF1PO10,11
D2S133820
D3S135814,17
D5S81811
D7S8209,12
D8S117911,14
D13S3178
D16S53911,12
D18S5113,16,17
D19S43314,16
D21S1131,31.2
FGA20
TH018
TPOX8,10
vWA16,17

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Publications

PubMed=29970484; DOI=10.1158/1535-7163.MCT-17-0733
Lepikhova T., Karhemo P.-R., Louhimo R., Yadav B., Murumagi A., Kulesskiy E., Kivento M., Sihto H., Grenman R., Syrjanen S.M., Kallioniemi O.-P., Aittokallio T., Wennerberg K., Joensuu H., Monni O.
Drug-sensitivity screening and genomic characterization of 45 HPV-negative head and neck carcinoma cell lines for novel biomarkers of drug efficacy.
Mol. Cancer Ther. 17:2060-2071(2018)

PubMed=30135316; DOI=10.1172/jci.insight.122204; PMCID=PMC6141174
Jamieson S.M.F., Tsai P., Kondratyev M.K., Budhani P., Liu A., Senzer N.N., Chiorean E.G., Jalal S.I., Nemunaitis J.J., Kee D., Shome A., Wong W.W., Li D., Poonawala-Lohani N., Kakadia P.M., Knowlton N.S., Lynch C.R.H., Hong C.R., Lee T.W., Grenman R., Caporiccio L., McKee T.D., Zaidi M., Butt S., Macann A.M.J., McIvor N.P., Chaplin J.M., Hicks K.O., Bohlander S.K., Wouters B.G., Hart C.P., Print C.G., Wilson W.R., Curran M.A., Hunter F.W.
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.
JCI Insight 3:e122204.1-e122204.19(2018)

DOI=10.1158/1538-7445.AM2020-507
Kondratyev M.K., Pesic A., Dvorkin-Sheva A., Ketela T., Moffat J., Koritzinsky M., Wouters B.G.
Repurposing of FDA approved drugs for treatment of metastatic HNSCC.
Cancer Res. 80 Suppl. 16:507-507(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A7EB
Encyclopedic resources Wikidata; Q107117358
Gene expression databases GEO; GSM2883394
GEO; GSM2888857
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number7