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Cellosaurus UT-SCC-76A (CVCL_A7DZ)

[Text version]
Cell line name UT-SCC-76A
Synonyms University of Turku-Squamous Cell Carcinoma-76A
Accession CVCL_A7DZ
Resource Identification Initiative To cite this cell line use: UT-SCC-76A (RRID:CVCL_A7DZ)
Comments Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Caution: UT-SCC-76A and UT-SCC-76B are supposed to originate from the same patient but have totally different STR profiles.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A7EA ! UT-SCC-76B
Sex of cell Male
Age at sampling 52Y
Category Cancer cell line
STR profile Source(s): PubMed=30135316

Markers:
AmelogeninX
CSF1PO13
D2S133820,25
D3S135815
D5S81811
D7S8208,10
D8S117914,15
D13S31712,13
D16S53911,12
D18S5115
D19S43315,16
D21S1133.2
FGA22
TH016,7
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=29970484; DOI=10.1158/1535-7163.MCT-17-0733
Lepikhova T., Karhemo P.-R., Louhimo R., Yadav B., Murumagi A., Kulesskiy E., Kivento M., Sihto H., Grenman R., Syrjanen S.M., Kallioniemi O.-P., Aittokallio T., Wennerberg K., Joensuu H., Monni O.
Drug-sensitivity screening and genomic characterization of 45 HPV-negative head and neck carcinoma cell lines for novel biomarkers of drug efficacy.
Mol. Cancer Ther. 17:2060-2071(2018)

PubMed=30135316; DOI=10.1172/jci.insight.122204; PMCID=PMC6141174
Jamieson S.M.F., Tsai P., Kondratyev M.K., Budhani P., Liu A., Senzer N.N., Chiorean E.G., Jalal S.I., Nemunaitis J.J., Kee D., Shome A., Wong W.W., Li D., Poonawala-Lohani N., Kakadia P.M., Knowlton N.S., Lynch C.R.H., Hong C.R., Lee T.W., Grenman R., Caporiccio L., McKee T.D., Zaidi M., Butt S., Macann A.M.J., McIvor N.P., Chaplin J.M., Hicks K.O., Bohlander S.K., Wouters B.G., Hart C.P., Print C.G., Wilson W.R., Curran M.A., Hunter F.W.
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.
JCI Insight 3:e122204.1-e122204.19(2018)

DOI=10.1158/1538-7445.AM2020-507
Kondratyev M.K., Pesic A., Dvorkin-Sheva A., Ketela T., Moffat J., Koritzinsky M., Wouters B.G.
Repurposing of FDA approved drugs for treatment of metastatic HNSCC.
Cancer Res. 80 Suppl. 16:507-507(2020)

Cross-references
Encyclopedic resources Wikidata; Q107117381
Gene expression databases GEO; GSM2883387
GEO; GSM2888850
Entry history
Entry creation20-May-2021
Last entry update10-Apr-2025
Version number5