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Cellosaurus UT-SCC-74A (CVCL_A7DX)

[Text version]
Cell line name UT-SCC-74A
Synonyms University of Turku-Squamous Cell Carcinoma-74A
Accession CVCL_A7DX
Resource Identification Initiative To cite this cell line use: UT-SCC-74A (RRID:CVCL_A7DX)
Comments Omics: Array-based CGH.
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A7DY ! UT-SCC-74B
Sex of cell Male
Age at sampling 31Y
Category Cancer cell line
STR profile Source(s): PubMed=30135316

Markers:
AmelogeninX,Y
CSF1PO10,13
D2S133818,19
D3S135815,16
D5S81811,12
D7S82010
D8S117910,12
D13S31712,14
D16S53911,12
D18S5116
D19S43315,16
D21S1127
FGA27
TH018
TPOX8
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=29970484; DOI=10.1158/1535-7163.MCT-17-0733
Lepikhova T., Karhemo P.-R., Louhimo R., Yadav B., Murumagi A., Kulesskiy E., Kivento M., Sihto H., Grenman R., Syrjanen S.M., Kallioniemi O.-P., Aittokallio T., Wennerberg K., Joensuu H., Monni O.
Drug-sensitivity screening and genomic characterization of 45 HPV-negative head and neck carcinoma cell lines for novel biomarkers of drug efficacy.
Mol. Cancer Ther. 17:2060-2071(2018)

PubMed=30135316; DOI=10.1172/jci.insight.122204; PMCID=PMC6141174
Jamieson S.M.F., Tsai P., Kondratyev M.K., Budhani P., Liu A., Senzer N.N., Chiorean E.G., Jalal S.I., Nemunaitis J.J., Kee D., Shome A., Wong W.W., Li D., Poonawala-Lohani N., Kakadia P.M., Knowlton N.S., Lynch C.R.H., Hong C.R., Lee T.W., Grenman R., Caporiccio L., McKee T.D., Zaidi M., Butt S., Macann A.M.J., McIvor N.P., Chaplin J.M., Hicks K.O., Bohlander S.K., Wouters B.G., Hart C.P., Print C.G., Wilson W.R., Curran M.A., Hunter F.W.
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.
JCI Insight 3:e122204.1-e122204.19(2018)

DOI=10.1158/1538-7445.AM2020-507
Kondratyev M.K., Pesic A., Dvorkin-Sheva A., Ketela T., Moffat J., Koritzinsky M., Wouters B.G.
Repurposing of FDA approved drugs for treatment of metastatic HNSCC.
Cancer Res. 80 Suppl. 16:507-507(2020)

Cross-references
Encyclopedic resources Wikidata; Q107117378
Gene expression databases GEO; GSM2883385
GEO; GSM2888848
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number5