Cellosaurus cell line WS10901 (CVCL

Cellosaurus WS10901 (CVCL_A7CE)

Cross-references
Cell line name	WS10901
Accession	CVCL_A7CE
Resource Identification Initiative	To cite this cell line use: WS10901 (RRID:CVCL_A7CE)
Comments	Population: Japanese. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Caution: Indicated as originating from a 60 year old female in PubMed=9365237 and from a 43 year old female in PubMed=10543396. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:12791; WRN; Simple; p.Lys1046fs*14 (c.3139-1G>C) (IVS25-1G>C); ClinVar=VCV000005447; Zygosity=Heterozygous (PubMed=9365237; PubMed=10543396).
Disease	Werner syndrome (NCIt: C3447) Werner syndrome (ORDO: Orphanet_902)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	43Y
Category	Transformed cell line
Publications	PubMed=9365237; DOI=10.1038/sj.onc.1201377 Tahara H., Tokutake Y., Maeda S., Kataoka H., Watanabe T., Satoh M., Matsumoto T., Sugawara M., Ide T., Goto M., Furuichi Y., Sugimoto M. Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein-Barr virus. Oncogene 15:1911-1920(1997) PubMed=10543396; DOI=10.1007/s004399900151 Goto M., Yamabe Y., Shiratori M., Okada M., Kawabe T., Matsumoto T., Sugimoto M., Furuichi Y. Immunological diagnosis of Werner syndrome by down-regulated and truncated gene products. Hum. Genet. 105:301-307(1999)
Encyclopedic resources	Wikidata; Q107117497
Entry history
Entry creation	20-May-2021
Last entry update	19-Dec-2024
Version number	5