ID   MEF_Hsp47 KO-13
AC   CVCL_A7BE
DR   RCB; RCB5293
DR   Wikidata; Q107116340
RX   PubMed=10995453;
RX   PubMed=16525016;
CC   Knockout cell: Method=KO mouse; MGI; MGI:88283; Serpinh1.
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   8-9FD
CA   Spontaneously immortalized cell line
DT   Created: 20-05-21; Last updated: 29-06-23; Version: 6
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RX   PubMed=10995453; DOI=10.1083/jcb.150.6.1499; PMCID=PMC2150697;
RA   Nagai N., Hosokawa M., Itohara S., Adachi E., Matsushita T.,
RA   Hosokawa N., Nagata K.;
RT   "Embryonic lethality of molecular chaperone hsp47 knockout mice is
RT   associated with defects in collagen biosynthesis.";
RL   J. Cell Biol. 150:1499-1506(2000).
//
RX   PubMed=16525016; DOI=10.1091/mbc.e05-11-1065; PMCID=PMC1446091;
RA   Ishida Y., Kubota H., Yamamoto A., Kitamura A., Bachinger H.P.,
RA   Nagata K.;
RT   "Type I collagen in Hsp47-null cells is aggregated in endoplasmic
RT   reticulum and deficient in N-propeptide processing and
RT   fibrillogenesis.";
RL   Mol. Biol. Cell 17:2346-2355(2006).
//