Cellosaurus cell line RMS-YM (CVCL

Cellosaurus RMS-YM (CVCL_A792)

[Text version]

Cell line name

RMS-YM

Synonyms

RMSYM

Accession

CVCL_A792

Resource Identification Initiative

To cite this cell line use: RMS-YM (RRID:CVCL_A792)

Comments

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: ~30 hours (PubMed=1906291).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Urachus; UBERON=UBERON_0002068.

Sequence variations

Mutation; HGNC; HGNC:20893; BCOR; Simple; p.Arg1163Ter (c.3487C>T); ClinVar=VCV000954289; Zygosity=Homozygous (DepMap=ACH-002048).

Disease

Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

Category

Cancer cell line

STR profile

Source(s): RCB=RCB1695

Markers:

Amelogenin	X,Y
CSF1PO	11
D5S818	12,14
D7S820	10,11
D13S317	10,11
D16S539	11
TH01	9
TPOX	11
vWA	18

Publications

PubMed=1906291; DOI=10.1038/bjc.1991.193; PMCID=PMC1972520
Kubo K., Naoe T., Utsumi K.R., Ishiguro Y., Ueda K., Shiku H., Yamada K.
Cytogenetic and cellular characteristics of a human embryonal rhabdomyosarcoma cell line, RMS-YM.
Br. J. Cancer 63:879-884(1991)

PubMed=19235922; DOI=10.1002/gcc.20655
Missiaglia E., Selfe J., Hamdi M., Williamson D., Schaaf G., Fang C., Koster J., Summersgill B.M., Messahel B., Versteeg R., Pritchard-Jones K., Kool M., Shipley J.M.
Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: an approach to identify candidate genes involved in tumor development.
Genes Chromosomes Cancer 48:455-467(2009)

PubMed=23828214; DOI=10.3892/or.2013.2588
Yamamoto Y., Fukuda K., Fuchimoto Y., Matsuzaki Y., Saikawa Y., Kitagawa Y., Morikawa Y., Kuroda T.
Cetuximab promotes anticancer drug toxicity in rhabdomyosarcomas with EGFR amplification in vitro.
Oncol. Rep. 30:1081-1086(2013)

PubMed=23882450; DOI=10.3389/fonc.2013.00183; PMCID=PMC3713458
Hinson A.R.P., Jones R., Crose L.E.S., Belyea B.C., Barr F.G., Linardic C.M.
Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research: utility and pitfalls.
Front. Oncol. 3:183.1-183.12(2013)

Cross-references

Cell line collections (Providers)

RCB; RCB1695

Cell line databases/resources

CLO; CLO_0050151
DepMap; ACH-002048

Biological sample resources

BioSample; SAMN03472121

Encyclopedic resources

Wikidata; Q54950693

Gene expression databases

GEO; GSM219743

Polymorphism and mutation databases