ID   SCL-II
AC   CVCL_A790
SY   SCL II; SCL-2; SCL2
DR   cancercelllines; CVCL_A790
DR   CLS; 300497
DR   Cosmic; 740988
DR   Wikidata; Q54952440
RX   PubMed=6196111;
RX   PubMed=11992403;
CC   Population: Caucasian.
CC   Doubling time: ~40-50 hours (CLS=300497).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys132Asn (c.396G>T); ClinVar=VCV000634773; Zygosity=Unspecified (PubMed=11992403).
CC   Derived from site: In situ; Face, skin; UBERON=UBERON_1000021.
ST   Source(s): CLS=300497
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 8,12
ST   D16S539: 10,11
ST   D18S51: 17
ST   D21S11: 29
ST   D3S1358: 14
ST   D5S818: 9
ST   D7S820: 8,12
ST   D8S1179: 12,13
ST   FGA: 26
ST   Penta D: 9,13
ST   Penta E: 13
ST   TH01: 8
ST   TPOX: 8,11
ST   vWA: 15,17
DI   NCIt; C4819; Skin squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   91Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 19
//
RX   PubMed=6196111;
RA   Tilgen W., Boukamp P., Breitkreutz D., Dzarlieva-Petrusevska R.T.,
RA   Engstner M., Haag D., Fusenig N.E.;
RT   "Preservation of morphological, functional, and karyotypic traits
RT   during long-term culture and in vivo passage of two human skin
RT   squamous cell carcinomas.";
RL   Cancer Res. 43:5995-6011(1983).
//
RX   PubMed=11992403; DOI=10.1002/ijc.10321;
RA   Popp S., Waltering S., Herbst C., Moll I., Boukamp P.;
RT   "UV-B-type mutations and chromosomal imbalances indicate common
RT   pathways for the development of Merkel and skin squamous cell
RT   carcinomas.";
RL   Int. J. Cancer 99:352-360(2002).
//