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Cellosaurus HEK293S (CVCL_A784)

[Text version]
Cell line name HEK293S
Synonyms HEK-293S; 293S
Accession CVCL_A784
Resource Identification Initiative To cite this cell line use: HEK293S (RRID:CVCL_A784)
Comments Characteristics: Adapted to growth in suspension.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Omics: Genome sequenced.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Children:
CVCL_A785 (HEK293S GnTI-)CVCL_4V94 (HEK293SF)CVCL_3712 (HKB-11)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Web pages http://hek293genome.org/v2/
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/2/cell-lines-detail-42.html
Publications

PubMed=8876162; DOI=10.1073/pnas.93.21.11487; PMCID=PMC38084
Reeves P.J., Thurmond R.L., Khorana H.G.
Structure and function in rhodopsin: high level expression of a synthetic bovine opsin gene and its mutants in stable mammalian cell lines.
Proc. Natl. Acad. Sci. U.S.A. 93:11487-11492(1996)

PubMed=10736692; DOI=10.1016/S0076-6879(00)15833-1
Sullivan J.M., Satchwell M.F.
Development of stable cell lines expressing high levels of point mutants of human opsin for biochemical and biophysical studies.
Methods Enzymol. 315:30-58(2000)

PubMed=25182477; DOI=10.1038/ncomms5767; PMCID=PMC4166678
Lin Y.-C., Boone M., Meuris L., Lemmens I., Van Roy N., Soete A., Reumers J., Moisse M., Plaisance S., Drmanac R., Chen J., Speleman F., Lambrechts D., Van de Peer Y., Tavernier J., Callewaert N.
Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations.
Nat. Commun. 5:4767.1-4767.12(2014)

DOI=10.13005/bpj/1414
Yuan J., Xu W.W.-Y., Jiang S.Y.-L., Yu H.X.-Y., Poon H.-F.
The scattered twelve tribes of HEK293.
Biomed. Pharmacol. J. 11:621-623(2018)

Cross-references
Anatomy/cell type resources BTO; BTO:0006453
Biological sample resources BioSamples; SAMEA2168959
Encyclopedic resources Wikidata; Q54882484
Experimental variables resources EFO; EFO_0022515
Entry history
Entry creation06-Jun-2012
Last entry update10-Sep-2024
Version number17