ID   SMS-CTR
AC   CVCL_A770
SY   SMS_CTR; SMSCTR
DR   cancercelllines; CVCL_A770
DR   Cell_Model_Passport; SIDM01337
DR   Cosmic; 802048
DR   Cosmic; 1097752
DR   Cosmic; 1718105
DR   Cosmic; 2355930
DR   DepMap; ACH-001196
DR   Wikidata; Q54954985
RX   CelloPub=CLPUB00569;
RX   PubMed=2302710;
RX   PubMed=8275086;
RX   PubMed=21948088;
RX   PubMed=22142829;
RX   PubMed=23882450;
RX   PubMed=28196595;
WW   https://tcpaportal.org/mclp/
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: MD Anderson Cell Lines Project.
CC   From: Reynolds C.P.; Children's Hospital of Los Angeles; Los Angeles; USA.
CC   Sequence variation: Mutation; HGNC; 5173; HRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000012601; Zygosity=Homozygous (PubMed=22142829; DepMap=ACH-001196).
CC   Omics: Deep exome analysis.
CC   Omics: Protein expression by reverse-phase protein arrays.
ST   Source(s): COG; PubMed=21948088
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 11
ST   D16S539: 10,11
ST   D18S51: 13
ST   D19S433: 14
ST   D21S11: 29,31.2
ST   D2S1338: 24
ST   D3S1358: 17
ST   D5S818: 12
ST   D7S820: 8,11
ST   D8S1179: 10,12
ST   FGA: 21,22
ST   TH01: 6
ST   TPOX: 8,12
ST   vWA: 18,19
DI   NCIt; C8971; Embryonal rhabdomyosarcoma
DI   ORDO; Orphanet_99757; Embryonal rhabdomyosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   1Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 02-05-24; Version: 19
//
RX   CelloPub=CLPUB00569;
RA   Dickman P.S., Tsokos M.G., Triche T.J.;
RT   "Biology of rhabdomyosarcoma: cell culture, xenografts, and animal
RT   models.";
RL   (In) Rhabdomyosarcoma and related tumors in children and adolescents; Maurer H.M., Ruymann F.B., Pochedly C.E. (eds.); pp.49-88; CRC Press; Boca Raton (1991).
//
RX   PubMed=2302710;
RA   Ozkaynak M.F., Nolta J., Parkman R.;
RT   "In vitro purging of human rhabdomyosarcoma cells using
RT   4-hydroperoxycyclophosphamide.";
RL   Cancer Res. 50:1455-1458(1990).
//
RX   PubMed=8275086; DOI=10.1038/ng1193-230;
RA   Galili N., Davis R.J., Fredericks W.J., Mukhopadhyay S.,
RA   Rauscher F.J. III, Emanuel B.S., Rovera G., Barr F.G.;
RT   "Fusion of a fork head domain gene to PAX3 in the solid tumour
RT   alveolar rhabdomyosarcoma.";
RL   Nat. Genet. 5:230-235(1993).
//
RX   PubMed=21948088; DOI=10.1158/1078-0432.CCR-11-1004;
RA   Belyea B.C., Naini S., Bentley R.C., Linardic C.M.;
RT   "Inhibition of the Notch-Hey1 axis blocks embryonal rhabdomyosarcoma
RT   tumorigenesis.";
RL   Clin. Cancer Res. 17:7324-7336(2011).
//
RX   PubMed=22142829; DOI=10.1158/1078-0432.CCR-11-2056;
RA   Shukla N., Ameur N., Yilmaz I., Nafa K., Lau C.-Y., Marchetti A.,
RA   Borsu L., Barr F.G., Ladanyi M.;
RT   "Oncogene mutation profiling of pediatric solid tumors reveals
RT   significant subsets of embryonal rhabdomyosarcoma and neuroblastoma
RT   with mutated genes in growth signaling pathways.";
RL   Clin. Cancer Res. 18:748-757(2012).
//
RX   PubMed=23882450; DOI=10.3389/fonc.2013.00183;
RA   Hinson A.R.P., Jones R., Crose L.E.S., Belyea B.C., Barr F.G.,
RA   Linardic C.M.;
RT   "Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research:
RT   utility and pitfalls.";
RL   Front. Oncol. 3:183.1-183.12(2013).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005;
RA   Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P.,
RA   Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L.,
RA   Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D.,
RA   Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B.,
RA   Liang H.;
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//