ID   SK-PN-LI
AC   CVCL_A748
SY   SK-PNET-Li; SKPNETLI
DR   cancercelllines; CVCL_A748
DR   Cosmic; 1078389
DR   Cosmic; 2228234
DR   Wikidata; Q54954520
RX   DOI=10.1016/B978-0-12-333530-2.50006-X;
RX   PubMed=2987426;
RX   PubMed=3024811;
RX   PubMed=8040301;
RX   PubMed=25010205;
RX   PubMed=28196595;
WW   https://tcpaportal.org/mclp/
CC   Part of: MD Anderson Cell Lines Project.
CC   From: Memorial Sloan Kettering Cancer Center; New York; USA.
CC   Sequence variation: Gene fusion; HGNC; 3446; ERG + HGNC; 3508; EWSR1; Name(s)=EWSR1-ERG, EWS-ERG (PubMed=8040301; PubMed=25010205).
CC   Sequence variation: Mutation; HGNC; 11355; STAG2; Simple; p.Ser704fs; Zygosity=Unspecified (PubMed=25010205).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Val272Leu (c.814G>T); ClinVar=VCV000012358; Zygosity=Unspecified (PubMed=25010205).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (PubMed=25010205).
CC   Omics: Protein expression by reverse-phase protein arrays.
CC   Omics: Transcriptome analysis by RNAseq.
ST   Source(s): PubMed=25010205
ST   Amelogenin: X,Y
ST   CSF1PO: 10
ST   D13S317: 9,11
ST   D16S539: 12
ST   D18S51: 16,20
ST   D19S433: 14,16
ST   D21S11: 33.2
ST   D2S1338: 17,21
ST   D3S1358: 15
ST   D5S818: 12
ST   D7S820: 10,12
ST   D8S1179: 12,14
ST   FGA: 21,22
ST   TH01: 6,8
ST   TPOX: 8,12
ST   vWA: 14,18
DI   NCIt; C3716; Primitive neuroectodermal tumor
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   3Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 18
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RX   DOI=10.1016/B978-0-12-333530-2.50006-X;
RA   Israel M.A., Thiele C.J.;
RT   "Tumor cell lines of the peripheral nervous system.";
RL   (In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.43-78; Academic Press; New York (1994).
//
RX   PubMed=2987426; DOI=10.1007/BF00165170;
RA   Helson L., Helson C.;
RT   "Human neuroblastoma cells and 13-cis-retinoic acid.";
RL   J. Neurooncol. 3:39-41(1985).
//
RX   PubMed=3024811; DOI=10.1016/0165-4608(87)90084-7;
RA   Potluri V.R., Gilbert F., Helsen C., Helson L.;
RT   "Primitive neuroectodermal tumor cell lines: chromosomal analysis of
RT   five cases.";
RL   Cancer Genet. Cytogenet. 24:75-86(1987).
//
RX   PubMed=8040301; DOI=10.1172/JCI117360;
RA   Giovannini M., Biegel J.A., Serra M., Wang J.-Y., Wei Y.-L.H., Nycum L.,
RA   Emanuel B.S., Evans G.A.;
RT   "EWS-erg and EWS-Fli1 fusion transcripts in Ewing's sarcoma and
RT   primitive neuroectodermal tumors with variant translocations.";
RL   J. Clin. Invest. 94:489-496(1994).
//
RX   PubMed=25010205; DOI=10.1371/journal.pgen.1004475;
RA   Brohl A.S., Solomon D.A., Chang W., Wang J.-J., Song Y., Sindiri S.,
RA   Patidar R., Hurd L., Chen L., Shern J.F., Liao H.-L., Wen X.-Y.,
RA   Gerard J., Kim J.-S., Lopez Guerrero J.A., Machado I., Wai D.H.,
RA   Picci P., Triche T.J., Horvai A.E., Miettinen M.M., Wei J.S.,
RA   Catchpoole D., Llombart-Bosch A., Waldman T., Khan J.;
RT   "The genomic landscape of the Ewing sarcoma family of tumors reveals
RT   recurrent STAG2 mutation.";
RL   PLoS Genet. 10:E1004475-E1004475(2014).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005;
RA   Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P.,
RA   Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L.,
RA   Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D.,
RA   Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B.,
RA   Liang H.;
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//