ID   VAMT-1
AC   CVCL_A731
SY   VAMT 1; VAMT1; VAMT
DR   BioSamples; SAMEA100992
DR   cancercelllines; CVCL_A731
DR   Cosmic; 733834
DR   Cosmic; 1522779
DR   Cosmic; 1541209
DR   GEO; GSM726285
DR   IARC_TP53; 23638
DR   Progenetix; CVCL_A731
DR   Wikidata; Q54992937
RX   CelloPub=CLPUB00125;
RX   PubMed=1568228;
RX   PubMed=21642991;
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=21642991).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=1568228).
CC   Omics: SNP array analysis.
DI   NCIt; C45663; Pleural sarcomatoid mesothelioma
DI   ORDO; Orphanet_50251; Pleural mesothelioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 17
//
RX   CelloPub=CLPUB00125;
RA   Tibbetts L.M., Chu M.Y., Spremulli E.N., Leduc E.H., Calabresi P.;
RT   "Loss and restoration of tumorigenicity in a human mesothelioma cell
RT   line.";
RL   Proc. Am. Assoc. Cancer Res. 25:45.176-45.176(1984).
//
RX   PubMed=1568228;
RA   Metcalf R.A., Welsh J.A., Bennett W.P., Seddon M.B., Lehman T.A.,
RA   Pelin-Enlund K., Linnainmaa K., Tammilehto L., Mattson K., Gerwin B.I.,
RA   Harris C.C.;
RT   "p53 and Kirsten-ras mutations in human mesothelioma cell lines.";
RL   Cancer Res. 52:2610-2615(1992).
//
RX   PubMed=21642991; DOI=10.1038/ng.855; PMCID=PMC4643098;
RA   Bott M.J., Brevet M., Taylor B.S., Shimizu S., Ito T., Wang L.,
RA   Creaney J., Lake R.A., Zakowski M.F., Reva B., Sander C., Delsite R.,
RA   Powell S.N., Zhou Q., Shen R.-L., Olshen A.B., Rusch V.W., Ladanyi M.;
RT   "The nuclear deubiquitinase BAP1 is commonly inactivated by somatic
RT   mutations and 3p21.1 losses in malignant pleural mesothelioma.";
RL   Nat. Genet. 43:668-672(2011).
//