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Cellosaurus UKRV-Mel-38 (CVCL_A730)

[Text version]
Cell line name UKRV-Mel-38
Accession CVCL_A730
Resource Identification Initiative To cite this cell line use: UKRV-Mel-38 (RRID:CVCL_A730)
Sequence variations
HLA typing Source: PubMed=15592718
Class I
HLA-AA*01:01,32:01
HLA-BB*08:01,44:02
HLA-CC*05:01,07:01:01
Class II
HLA-DPDPB1*02:01:02,04:01
HLA-DQDQB1*03:01:01,03:03:02
HLA-DRDRB1*04:01:01,15:01
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-112

Markers:
AmelogeninX
CSF1PO11
D3S135816
D5S81812
D7S8209,10
D13S31711,13
FGA23
TH018,9.3
TPOX8,10
vWA15,17

Run an STR similarity search on this cell line
Publications

PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966
Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello Osuna F., Dodi I.A., Lopez-Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G., Garrido F.
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=19340423; DOI=10.1007/s00262-009-0701-z; PMCID=PMC11030131
Mendez R., Aptsiauri N., Del Campo A., Maleno I., Cabrera T., Ruiz-Cabello Osuna F., Garrido F., Garcia-Lora A.
HLA and melanoma: multiple alterations in HLA class I and II expression in human melanoma cell lines from ESTDAB cell bank.
Cancer Immunol. Immunother. 58:1507-1515(2009)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L., Borg A., Pawelec G., Guldberg P.
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A730
ESTDAB; ESTDAB-112
Encyclopedic resources Wikidata; Q54990630
Polymorphism and mutation databases Cosmic; 2163823
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number16