Cellosaurus cell line UKRV-Mel-16 (CVCL

Cellosaurus UKRV-Mel-16 (CVCL_A715)

[Text version]

Cell line name

UKRV-Mel-16

Synonyms

UKRV-Mel-16a

Accession

CVCL_A715

Resource Identification Initiative

To cite this cell line use: UKRV-Mel-16 (RRID:CVCL_A715)

Comments

Derived from site: Metastatic; Hypodermis; UBERON=UBERON_0002072.
Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.

Sequence variations

Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).

Disease

Melanoma (NCIt: C3224)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

24Y

Category

Cancer cell line

STR profile

Source(s): ESTDAB=ESTDAB-180

Markers:

Amelogenin	X
CSF1PO	11,12
D3S1358	16
D5S818	9,12
D7S820	8
D13S317	13
FGA	26
TH01	6,9.3
TPOX	8
vWA	17,20

Publications

PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595
Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A., Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R., Schadendorf D.
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
PLoS ONE 2:E236-E236(2007)

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_A715
ESTDAB; ESTDAB-180

Encyclopedic resources

Wikidata; Q54990599

Polymorphism and mutation databases

Cosmic; 2686518

Entry history

Entry creation

06-Jun-2012

Last entry update

19-Dec-2024

Version number