ID   UKRV-Mel-15a
AC   CVCL_A713
SY   UKRV-Mel-15A
DR   cancercelllines; CVCL_A713
DR   Cosmic; 2163819
DR   ESTDAB; ESTDAB-107
DR   Wikidata; Q54990594
RX   PubMed=10594685;
RX   PubMed=15592718;
RX   PubMed=23851445;
CC   HLA typing: A*02:01,11:01; B*15:01:01:01,56:01; C*01:02,03:03; DPB1*04:01; DQB1*06:02,05:01; DRB1*01:01,15:01 (PubMed=15592718).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=23851445).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Unspecified (PubMed=23851445).
ST   Source(s): ESTDAB=ESTDAB-107
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11,12
ST   D3S1358: 15,16
ST   D5S818: 11
ST   D7S820: 8,12
ST   FGA: 21,22
ST   TH01: 6
ST   TPOX: 8,12
ST   vWA: 15,17
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_C397 ! UKRV-Mel-15b
OI   CVCL_C398 ! UKRV-Mel-15c
OI   CVCL_A714 ! UKRV-Mel-15d
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 16
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RX   PubMed=10594685; DOI=10.1046/j.1365-2567.1999.00902.x; PMCID=PMC2326956;
RA   Sun Y.-S., Moller P., Berking C., Schlupen E.-M., Volkenandt M.,
RA   Schadendorf D.;
RT   "In vivo selective expansion of a tumour-specific cytotoxic T-cell
RT   clone derived from peripheral blood of a melanoma patient after
RT   vaccination with gene-modified autologous tumour cells.";
RL   Immunology 98:535-540(1999).
//
RX   PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966;
RA   Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello Osuna F., Dodi I.A.,
RA   Lopez-Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G.,
RA   Garrido F.;
RT   "High frequency of homozygosity of the HLA region in melanoma cell
RT   lines reveals a pattern compatible with extensive loss of
RT   heterozygosity.";
RL   Cancer Immunol. Immunother. 54:141-148(2005).
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RX   PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006;
RA   Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L.,
RA   Borg A., Pawelec G., Guldberg P.;
RT   "Mutual exclusivity analysis of genetic and epigenetic drivers in
RT   melanoma identifies a link between p14 ARF and RARbeta signaling.";
RL   Mol. Cancer Res. 11:1166-1178(2013).
//