Cellosaurus cell line UKRV-Mel-14b (CVCL

Cellosaurus UKRV-Mel-14b (CVCL_A711)

[Text version]

Cell line name

UKRV-Mel-14b

Accession

CVCL_A711

Resource Identification Initiative

To cite this cell line use: UKRV-Mel-14b (RRID:CVCL_A711)

Comments

Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.

Sequence variations

Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).

Disease

Melanoma (NCIt: C3224)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_A710 ! UKRV-Mel-14a
CVCL_C409 ! UKRV-Mel-14c

Sex of cell

Female

Age at sampling

52Y

Category

Cancer cell line

STR profile

Source(s): ECACC=13012529; ESTDAB=ESTDAB-225

Markers:

Amelogenin	X
CSF1PO	12
D3S1358	15,16
D5S818	11,12
D7S820	8,10
D13S317	10,12
D16S539	11
FGA	25
TH01	7,9
TPOX	8,9
vWA	15,17

Publications

PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595
Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A., Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R., Schadendorf D.
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
PLoS ONE 2:E236-E236(2007)

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references

Cell line collections (Providers)

ECACC; 13012529

Cell line databases/resources

cancercelllines; CVCL_A711
ESTDAB; ESTDAB-225

Encyclopedic resources

Wikidata; Q54990572

Polymorphism and mutation databases

Cosmic; 1846700
Cosmic; 2686513

Entry history

Entry creation

06-Jun-2012

Last entry update

19-Dec-2024

Version number