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Cellosaurus UKRV-Mel-07 (CVCL_A706)

[Text version]
Cell line name UKRV-Mel-07
Synonyms UKRV-Mel-7; UKRV MEL7
Accession CVCL_A706
Resource Identification Initiative To cite this cell line use: UKRV-Mel-07 (RRID:CVCL_A706)
Comments Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (PubMed=23348503).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=7646526; DOI=10.1006/bbrc.1995.2187
Artuc M., Nurnberg W., Czarnetzki B.M., Schadendorf D.
Characterization of gene regulatory elements for selective gene expression in human melanoma cells.
Biochem. Biophys. Res. Commun. 213:699-705(1995)

PubMed=10594685; DOI=10.1046/j.1365-2567.1999.00902.x; PMCID=PMC2326956
Sun Y.-S., Moller P., Berking C., Schlupen E.-M., Volkenandt M., Schadendorf D.
In vivo selective expansion of a tumour-specific cytotoxic T-cell clone derived from peripheral blood of a melanoma patient after vaccination with gene-modified autologous tumour cells.
Immunology 98:535-540(1999)

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A706
Encyclopedic resources Wikidata; Q54990563
Polymorphism and mutation databases Cosmic; 972285
Cosmic; 1846694
Cosmic; 2686507
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number15