Cellosaurus cell line UKRV-Mel-06b (CVCL

Cellosaurus UKRV-Mel-06b (CVCL_A705)

[Text version]

Cell line name

UKRV-Mel-06b

Synonyms

UKRV-Mel-6b

Accession

CVCL_A705

Resource Identification Initiative

To cite this cell line use: UKRV-Mel-06b (RRID:CVCL_A705)

Comments

Derived from site: Metastatic; Hypodermis; UBERON=UBERON_0002072.
Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.

Sequence variations

Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).

Disease

Melanoma (NCIt: C3224)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_A704 ! UKRV-Mel-06a

Sex of cell

Female

Age at sampling

51Y

Category

Cancer cell line

STR profile

Source(s): ECACC=13012538; ESTDAB=ESTDAB-222

Markers:

Amelogenin	X
CSF1PO	7,11 (ESTDAB=ESTDAB-222) 11 (ECACC=13012538)
D3S1358	15,16
D5S818	11
D7S820	12,13
D13S317	11
D16S539	9,11
FGA	23
TH01	6
TPOX	8
vWA	18

Publications

PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595
Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A., Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R., Schadendorf D.
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
PLoS ONE 2:E236-E236(2007)

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references

Cell line collections (Providers)

ECACC; 13012538

Cell line databases/resources

cancercelllines; CVCL_A705
ESTDAB; ESTDAB-222

Encyclopedic resources

Wikidata; Q54990562

Polymorphism and mutation databases

Cosmic; 1846693
Cosmic; 2686505

Entry history

Entry creation

06-Jun-2012

Last entry update

19-Dec-2024

Version number