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Cellosaurus 40LB (CVCL_A6ZS)

[Text version]
Cell line name 40LB
Synonyms 3T3/40L/BAFF
Accession CVCL_A6ZS
Resource Identification Initiative To cite this cell line use: 40LB (RRID:CVCL_A6ZS)
Comments Characteristics: Can be used as feeder cells for B cell culture. Support efficient proliferation and survival of B cells (PubMed=21897376).
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:1344376; Tnfsf13b.
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:88337; Cd40lg.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_A6ZR (3T3/40L)
Sex of cell Sex unspecified
Age at sampling 14-17FD
Category Spontaneously immortalized cell line
Publications

PubMed=21897376; DOI=10.1038/ncomms1475
Nojima T., Haniuda K., Moutai T., Matsudaira M., Mizokawa S., Shiratori I., Azuma T., Kitamura D.
In-vitro derived germinal centre B cells differentially generate memory B or plasma cells in vivo.
Nat. Commun. 2:465.1-465.11(2011)

Cross-references
Cell line collections (Providers) RCB; RCB5304
Encyclopedic resources Wikidata; Q107113282
Entry history
Entry creation20-May-2021
Last entry update10-Sep-2024
Version number7