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Cellosaurus AQP4(E5415A-1H6-68) (CVCL_A6YZ)

[Text version]
Cell line name AQP4(E5415A-1H6-68)
Synonyms E5415A-1H6-68; E5415A
Accession CVCL_A6YZ
Resource Identification Initiative To cite this cell line use: AQP4(E5415A-1H6-68) (RRID:CVCL_A6YZ)
Comments Monoclonal antibody isotype: IgG2a, kappa.
Monoclonal antibody target: UniProtKB; P55088; Mouse Aqp4 (Note=Isoform M23).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2155 (P3/NS1/1-Ag4.1)
Category Hybridoma
Publications

PubMed=26637322; DOI=10.1186/s40478-015-0259-2; PMCID=PMC4670539
Kurosawa K., Misu T., Takai Y., Sato D.K., Takahashi T., Abe Y., Iwanari H., Ogawa R., Nakashima I., Fujihara K., Hamakubo T., Yasui M., Aoki M.
Severely exacerbated neuromyelitis optica rat model with extensive astrocytopathy by high affinity anti-aquaporin-4 monoclonal antibody.
Acta Neuropathol. Commun. 3:82.1-82.15(2015)

PubMed=28955892; DOI=10.1016/j.bbrep.2016.05.017; PMCID=PMC5613303
Huang P., Takai Y., Kusano-Arai O., Ramadhanti J., Iwanari H., Miyauchi T., Sakihama T., Han J.-Y., Aoki M., Hamakubo T., Fujihara K., Yasui M., Abe Y.
The binding property of a monoclonal antibody against the extracellular domains of aquaporin-4 directs aquaporin-4 toward endocytosis.
Biochem. Biophys. Rep. 7:77-83(2016)

Cross-references
Cell line collections (Providers) RCB; RCB4883
Encyclopedic resources Wikidata; Q107113371
Entry history
Entry creation20-May-2021
Last entry update10-Sep-2024
Version number5