Cellosaurus logo
expasy logo

Cellosaurus CHO hAQP4-M23 (CVCL_A6YT)

[Text version]
Cell line name CHO hAQP4-M23
Accession CVCL_A6YT
Resource Identification Initiative To cite this cell line use: CHO hAQP4-M23 (RRID:CVCL_A6YT)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:637; AQP4 (Note=Isoform M23).
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=23746426; DOI=10.1016/j.jneuroim.2013.03.003
Miyazaki-Komine K., Abe Y., Iwanari H., Suzuki Y., Kikuchi T., Ito T., Kato J., Kusano-Arai O., Takahashi T., Nishiyama S., Ikeshima-Kataoka H., Tsuji S., Arimitsu T., Kato Y., Sakihama T., Toyama Y., Fujihara K., Hamakubo T., Yasui M.
Establishment of monoclonal antibodies against the extracellular domain that block binding of NMO-IgG to AQP4.
J. Neuroimmunol. 260:107-116(2013)

PubMed=26398585; DOI=10.1111/bph.13340; PMCID=PMC4813391
Miyazaki-Komine K., Takai Y., Huang P., Kusano-Arai O., Iwanari H., Misu T., Koda K., Mitomo K., Sakihama T., Toyama Y., Fujihara K., Hamakubo T., Yasui M., Abe Y.
High avidity chimeric monoclonal antibodies against the extracellular domains of human aquaporin-4 competing with the neuromyelitis optica autoantibody, NMO-IgG.
Br. J. Pharmacol. 173:103-114(2016)

Cross-references
Encyclopedic resources Wikidata; Q107114655
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number7