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Cellosaurus AQP4(D15107-3D7-33) (CVCL_A6YQ)

[Text version]
Cell line name AQP4(D15107-3D7-33)
Synonyms D15107-3D7-33; D15107
Accession CVCL_A6YQ
Resource Identification Initiative To cite this cell line use: AQP4(D15107-3D7-33) (RRID:CVCL_A6YQ)
Comments Monoclonal antibody isotype: IgG2a, kappa.
Monoclonal antibody target: UniProtKB; P55087; Human AQP4 (Note=Isoform M23. Also reacts with mouse).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2155 (P3/NS1/1-Ag4.1)
Category Hybridoma
Publications

PubMed=23746426; DOI=10.1016/j.jneuroim.2013.03.003
Miyazaki-Komine K., Abe Y., Iwanari H., Suzuki Y., Kikuchi T., Ito T., Kato J., Kusano-Arai O., Takahashi T., Nishiyama S., Ikeshima-Kataoka H., Tsuji S., Arimitsu T., Kato Y., Sakihama T., Toyama Y., Fujihara K., Hamakubo T., Yasui M.
Establishment of monoclonal antibodies against the extracellular domain that block binding of NMO-IgG to AQP4.
J. Neuroimmunol. 260:107-116(2013)

PubMed=26637322; DOI=10.1186/s40478-015-0259-2; PMCID=PMC4670539
Kurosawa K., Misu T., Takai Y., Sato D.K., Takahashi T., Abe Y., Iwanari H., Ogawa R., Nakashima I., Fujihara K., Hamakubo T., Yasui M., Aoki M.
Severely exacerbated neuromyelitis optica rat model with extensive astrocytopathy by high affinity anti-aquaporin-4 monoclonal antibody.
Acta Neuropathol. Commun. 3:82.1-82.15(2015)

PubMed=26398585; DOI=10.1111/bph.13340; PMCID=PMC4813391
Miyazaki-Komine K., Takai Y., Huang P., Kusano-Arai O., Iwanari H., Misu T., Koda K., Mitomo K., Sakihama T., Toyama Y., Fujihara K., Hamakubo T., Yasui M., Abe Y.
High avidity chimeric monoclonal antibodies against the extracellular domains of human aquaporin-4 competing with the neuromyelitis optica autoantibody, NMO-IgG.
Br. J. Pharmacol. 173:103-114(2016)

Cross-references
Cell line collections (Providers) RCB; RCB4872
Encyclopedic resources Wikidata; Q107113367
Entry history
Entry creation20-May-2021
Last entry update10-Sep-2024
Version number5