ID   Tp276MG
AC   CVCL_A687
SY   TP276MG; Tp-276MG
DR   cancercelllines; CVCL_A687
DR   Cosmic; 849848
DR   Cosmic; 1610746
DR   Wikidata; Q54972828
RX   PubMed=2469512;
RX   PubMed=6601641;
RX   PubMed=10560660;
RX   PubMed=19435942;
CC   Sequence variation: Mutation; HGNC; 5382; IDH1; None_reported; -; Zygosity=- (PubMed=19435942).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.His93Tyr (c.277C>T); ClinVar=VCV000646993; Zygosity=Unspecified (PubMed=10560660).
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 14
//
RX   PubMed=2469512; DOI=10.1016/0006-8993(89)90190-X;
RA   Brismar T., Collins V.P.;
RT   "Inward rectifying potassium channels in human malignant glioma
RT   cells.";
RL   Brain Res. 480:249-258(1989).
//
RX   PubMed=6601641;
RA   Collins V.P.;
RT   "Cultured human glial and glioma cells.";
RL   Int. Rev. Exp. Pathol. 24:135-202(1983).
//
RX   PubMed=10560660; DOI=10.1097/00005072-199911000-00007;
RA   Schmidt E.E., Ichimura K., Goike H.M., Moshref A., Liu L.,
RA   Collins V.P.;
RT   "Mutational profile of the PTEN gene in primary human astrocytic
RT   tumors and cultivated xenografts.";
RL   J. Neuropathol. Exp. Neurol. 58:1170-1183(1999).
//
RX   PubMed=19435942; DOI=10.1215/15228517-2009-025; PMCID=PMC2743214;
RA   Ichimura K., Pearson D.M., Kocialkowski S., Backlund L.M., Chan R.,
RA   Jones D.T.W., Collins V.P.;
RT   "IDH1 mutations are present in the majority of common adult gliomas
RT   but rare in primary glioblastomas.";
RL   Neuro-oncol. 11:341-347(2009).
//