ID   PM-WK
AC   CVCL_A665
AS   CVCL_W800
SY   PMWK; WK
DR   EFO; EFO_0022371
DR   ATCC; CRL-2624
DR   Cosmic; 706111
DR   Cosmic; 1054843
DR   Cosmic; 1507621
DR   Cosmic; 2233665
DR   Cosmic; 2630485
DR   Wikidata; Q54947604
RX   PubMed=1867326;
RX   PubMed=7680081;
RX   PubMed=8429233;
RX   PubMed=9141475;
RX   PubMed=9692547;
RX   PubMed=10766161;
RX   PubMed=11606052;
RX   PubMed=17308088;
CC   Sequence variation: Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Homozygous (PubMed=9692547; PubMed=10766161).
CC   Discontinued: ATCC; CRL-2624; true.
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
ST   Source(s): ATCC=CRL-2624
ST   Amelogenin: X
ST   CSF1PO: 9
ST   D13S317: 8
ST   D16S539: 11
ST   D5S818: 12
ST   D7S820: 9,12
ST   TH01: 7
ST   TPOX: 7
ST   vWA: 17
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 17
//
RX   PubMed=1867326; PMCID=PMC1886079;
RA   Byers H.R., Etoh T., Doherty J.R., Sober A.J., Mihm M.C. Jr.;
RT   "Cell migration and actin organization in cultured human primary,
RT   recurrent cutaneous and metastatic melanoma. Time-lapse and image
RT   analysis.";
RL   Am. J. Pathol. 139:423-435(1991).
//
RX   PubMed=7680081;
RA   Vink J., Thomas L., Etoh T., Bruijn J.A., Mihm M.C. Jr.,
RA   Gattoni-Celli S., Byers H.R.;
RT   "Role of beta-1 integrins in organ specific adhesion of melanoma cells
RT   in vitro.";
RL   Lab. Invest. 68:192-203(1993).
//
RX   PubMed=8429233; DOI=10.1111/1523-1747.ep12462776;
RA   Thomas L., Etoh T., Stamenkovic I., Mihm M.C. Jr., Byers H.R.;
RT   "Migration of human melanoma cells on hyaluronate is related to CD44
RT   expression.";
RL   J. Invest. Dermatol. 100:115-120(1993).
//
RX   PubMed=9141475; DOI=10.1016/S0014-5793(97)00290-1;
RA   Katagata Y., Kondo S.;
RT   "Keratin expression and its significance in five cultured melanoma
RT   cell lines derived from primary, recurrent and metastasized
RT   melanomas.";
RL   FEBS Lett. 407:25-31(1997).
//
RX   PubMed=9692547; DOI=10.1038/sj.onc.1201881;
RA   Tsao H., Zhang X., Benoit E., Haluska F.G.;
RT   "Identification of PTEN/MMAC1 alterations in uncultured melanomas and
RT   melanoma cell lines.";
RL   Oncogene 16:3397-3402(1998).
//
RX   PubMed=10766161;
RA   Tsao H., Zhang X., Fowlkes K., Haluska F.G.;
RT   "Relative reciprocity of NRAS and PTEN/MMAC1 alterations in cutaneous
RT   melanoma cell lines.";
RL   Cancer Res. 60:1800-1804(2000).
//
RX   PubMed=11606052; DOI=10.1006/bbrc.2001.5789;
RA   Hoashi T., Kadono T., Kikuchi K., Etoh T., Tamaki K.;
RT   "Differential growth regulation in human melanoma cell lines by TIMP-1
RT   and TIMP-2.";
RL   Biochem. Biophys. Res. Commun. 288:371-379(2001).
//
RX   PubMed=17308088; DOI=10.1158/0008-5472.CAN-06-3311;
RA   Shields J.M., Thomas N.E., Cregger M., Berger A.J., Leslie M.,
RA   Torrice C., Hao H.-L., Penland S., Arbiser J.L., Scott G.A., Zhou T.,
RA   Bar-Eli M., Bear J.E., Der C.J., Kaufmann W.K., Rimm D.L.,
RA   Sharpless N.E.;
RT   "Lack of extracellular signal-regulated kinase mitogen-activated
RT   protein kinase signaling shows a new type of melanoma.";
RL   Cancer Res. 67:1502-1512(2007).
//