Cellosaurus cell line MZ-PC-4 (CVCL

Cellosaurus MZ-PC-4 (CVCL_A659)

Cross-references
Cell line name	MZ-PC-4
Synonyms	MZPC-4; MainZ-Pancreatic Cancer-4
Accession	CVCL_A659
Resource Identification Initiative	To cite this cell line use: MZ-PC-4 (RRID:CVCL_A659)
Comments	From: Knuth, Alexander; Johannes Gutenberg Universitat; Mainz; Germany.
Sequence variations	Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=8026879). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys135Trp (c.405C>G); ClinVar=VCV000376561; Zygosity=Unspecified (PubMed=8026879).
Disease	Pancreatic carcinoma (NCIt: C207229)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=8026879; DOI=10.1002/ijc.2910580207 Berrozpe G., Schaeffer J., Peinado M.A., Real F.X., Perucho M. Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer. Int. J. Cancer 58:185-191(1994) PubMed=9665481; DOI=10.1016/S0002-9440(10)65561-7; PMCID=PMC1852940 Paciucci R., Vila M.R., Adell T., Diaz V.M., Tora M., Nakamura T., Real F.X. Activation of the urokinase plasminogen activator/urokinase plasminogen activator receptor system and redistribution of E-cadherin are associated with hepatocyte growth factor-induced motility of pancreas tumor cells overexpressing Met. Am. J. Pathol. 153:201-212(1998)
Cell line databases/resources	cancercelllines; CVCL_A659
Encyclopedic resources	Wikidata; Q54907233
Polymorphism and mutation databases	Cosmic; 948734 IARC_TP53; 3381
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	16