ID   MZ-PC-2
AC   CVCL_A658
SY   MZPC-2; MainZ-Pancreatic Cancer-2
DR   cancercelllines; CVCL_A658
DR   Cosmic; 948733
DR   IARC_TP53; 3380
DR   Wikidata; Q54907231
RX   PubMed=8026879;
RX   PubMed=8514455;
RX   PubMed=9665481;
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Unspecified (PubMed=8026879).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (PubMed=8026879).
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
DI   NCIt; C8294; Pancreatic adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   24Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 16
//
RX   PubMed=8026879; DOI=10.1002/ijc.2910580207;
RA   Berrozpe G., Schaeffer J., Peinado M.A., Real F.X., Perucho M.;
RT   "Comparative analysis of mutations in the p53 and K-ras genes in
RT   pancreatic cancer.";
RL   Int. J. Cancer 58:185-191(1994).
//
RX   PubMed=8514455; DOI=10.1002/ijc.2910540419;
RA   Wolfel T., Herr W., Coulie P.G., Schmitt U.,
RA   Meyer zum Buschenfelde K.-H., Knuth A.;
RT   "Lysis of human pancreatic adenocarcinoma cells by autologous
RT   HLA-class I-restricted cytolytic T-lymphocyte (CTL) clones.";
RL   Int. J. Cancer 54:636-644(1993).
//
RX   PubMed=9665481; DOI=10.1016/S0002-9440(10)65561-7; PMCID=PMC1852940;
RA   Paciucci R., Vila M.R., Adell T., Diaz V.M., Tora M., Nakamura T.,
RA   Real F.X.;
RT   "Activation of the urokinase plasminogen activator/urokinase
RT   plasminogen activator receptor system and redistribution of E-cadherin
RT   are associated with hepatocyte growth factor-induced motility of
RT   pancreas tumor cells overexpressing Met.";
RL   Am. J. Pathol. 153:201-212(1998).
//