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Cellosaurus JBL-2 (CVCL_A630)

[Text version]
Cell line name JBL-2
Synonyms JBL2; Japanese Burkitt's Lymphoma 2
Accession CVCL_A630
Resource Identification Initiative To cite this cell line use: JBL-2 (RRID:CVCL_A630)
Comments Population: Japanese.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 29Y
Category Cancer cell line
Publications

PubMed=467575; DOI=10.1007/BF01968217
Isao Miyoshi, Shunkichi Hiraki, Ikuro Kimura, Kanji Miyamoto, Jiro Sato;
2/8 translocation in a Japanese Burkitt's lymphoma.
Experientia 35:742-743(1979)

PubMed=7464876; DOI=10.1056/NEJM198103193041221
Isao Miyoshi, Kazuhide Hamasaki, Kanji Miyamoto, Kei Nagase, Kouji Narahara, Koichi Kitajima, Ikuro Kimura, Jiro Sato;
Chromosome translocations in Burkitt's lymphoma.
N. Engl. J. Med. 304:734-734(1981)

PubMed=6286514; DOI=10.1002/ijc.2910290609
Joelle Wiels, Gilbert Marcel Lenoir, Marc Fellous, Marc Lipinski, Jean-Claude Salomon, Cecile Tetaud, Thomas Tursz;
A monoclonal antibody with anti-Burkitt lymphoma specificity. I Analysis of human haematopoietic and lymphoid cell lines.
Int. J. Cancer 29:653-658(1982)

PubMed=6806672; DOI=10.1038/298474a0
Gilbert Marcel Lenoir, Jean-Louis Preud'homme, Alain Bernheim, Roland Berger;
Correlation between immunoglobulin light chain expression and variant translocation in Burkitt's lymphoma.
Nature 298:474-476(1982)

PubMed=7064731; DOI=10.18926/AMO/30706
Kazuhide Hamasaki;
Chromosome abnormalities in Japanese Burkitt lymphoma cell lines.
Acta Med. Okayama 36:23-38(1982)

PubMed=6327071; DOI=10.1016/0092-8674(84)90381-7
Rebecca Taub, Kathleen Kelly, James Battey, Samuel Arch Latt, Gilbert Marcel Lenoir, Umadevi Tantravahi, Zhi-Ming Tu, Philip Leder;
A novel alteration in the structure of an activated c-myc gene in a variant t(2;8) Burkitt lymphoma.
Cell 37:511-520(1984)

PubMed=3024964; DOI=10.1002/j.1460-2075.1986.tb04578.x; PMCID=PMC1167233
Mark Graham, Jerry McKee Adams;
Chromosome 8 breakpoint far 3' of the c-myc oncogene in a Burkitt's lymphoma 2;8 variant translocation is equivalent to the murine pvt-1 locus.
EMBO J. 5:2845-2851(1986)

PubMed=3026973; DOI=10.1002/ijc.2910390215
Barbro Ehlin-Henriksson, Agneta Manneborg-Sandlund, George Klein;
Expression of B-cell-specific markers in different Burkitt lymphoma subgroups.
Int. J. Cancer 39:211-218(1987)

PubMed=3027441; DOI=10.1093/jnci/78.2.235
Jacques H.M. Cohen, Jean-Pierre Revillard, Jean-Pierre Magaud, Gilbert Marcel Lenoir, Michele Vuillaume, Anne-Marie Manel, Claude Vincent, Paul-Andre Bryon;
B-cell maturation stages of Burkitt's lymphoma cell lines according to Epstein-Barr virus status and type of chromosome translocation.
J. Natl. Cancer Inst. 78:235-242(1987)

PubMed=2847931; DOI=10.1002/eji.1830181003
Michel Cogne, Samir Mounir, Jean-Louis Preud'homme, Francois Nau, Paul Guglielmi;
Burkitt's lymphoma cell lines producing truncated mu immunoglobulin heavy chains lacking part of the variable region.
Eur. J. Immunol. 18:1485-1489(1988)

PubMed=2470097; DOI=10.1073/pnas.86.9.3257; PMCID=PMC287109
Emma Shtivelman, Berthold Henglein, Peter Groitl, Martin Lipp, John Michael Bishop;
Identification of a human transcription unit affected by the variant chromosomal translocations 2;8 and 8;22 of Burkitt lymphoma.
Proc. Natl. Acad. Sci. U.S.A. 86:3257-3260(1989)

PubMed=1395095; DOI=10.1111/j.1365-2249.1992.tb05846.x; PMCID=PMC1554548
Isabelle Leduc, Jean-Louis Preud'homme, Michel Cogne;
Structure and expression of the mb-1 transcript in human lymphoid cells.
Clin. Exp. Immunol. 90:141-146(1992)

PubMed=9473234; DOI=10.1182/blood.V91.5.1680
Ulf Klangby, Ismail Okan, Kristinn Petur Magnusson, Martin Wendland, Peter Lind, Klas G. Wiman;
p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma.
Blood 91:1680-1687(1998)

PubMed=22120970; DOI=10.1002/gcc.21915
Hannes Kroenlein, Stefan Schwartz, Richard Reinhardt, Harald Rieder, Mara Molkentin, Nicola Gokbuget, Dieter Hoelzer, Eckhard Thiel, Thomas Burmeister;
Molecular analysis of the t(2;8)/MYC-IGK translocation in high-grade lymphoma/leukemia by long-distance inverse PCR.
Genes Chromosomes Cancer 51:290-299(2012)

PubMed=24590883; DOI=10.1002/gcc.22161
Eva-Maria Murga Penas, Georgia Schilling, Petra Behrmann, Marianne Klokow, Eik Vettorazzi, Carsten Bokemeyer, Judith Dierlamm;
Comprehensive cytogenetic and molecular cytogenetic analysis of 44 Burkitt lymphoma cell lines: secondary chromosomal changes characterization, karyotypic evolution, and comparison with primary samples.
Genes Chromosomes Cancer 53:497-515(2014)

Cross-references
Encyclopedic resources Wikidata; Q54898529
Polymorphism and mutation databases Cosmic; 931123
Entry history
Entry creation06-Jun-2012
Last entry update14-Aug-2025
Version number18