Cellosaurus logo
expasy logo

Cellosaurus JW18DOX (CVCL_A5UX)

[Text version]
Cell line name JW18DOX
Synonyms JW18-DOX; JW18TET
Accession CVCL_A5UX
Resource Identification Initiative To cite this cell line use: JW18DOX (RRID:CVCL_A5UX)
Comments Group: Insect cell line.
Characteristics: Expresses a Jupiter-GFP fusion protein.
Characteristics: Cured of Wolbachia infection through doxycycline treatment.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Species of origin Drosophila melanogaster (Fruit fly) (NCBI Taxonomy: 7227)
Hierarchy Parent: CVCL_A5UW (JW18)
Sex of cell Sex unspecified
Age at sampling Embryonic stage
Category Spontaneously immortalized cell line
Publications

PubMed=23028321; DOI=10.1371/journal.ppat.1002922; PMCID=PMC3447747
Serbus L.R., Landmann F., Bray W.M., White P.M., Ruybal J., Lokey R.S., Debec A., Sullivan W.
A cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets Wolbachia.
PLoS Pathog. 8:E1002922-E1002922(2012)

PubMed=28159754; DOI=10.1534/genetics.116.198903; PMCID=PMC5378107
White P.M., Serbus L.R., Debec A., Codina A., Bray W.M., Guichet A., Lokey R.S., Sullivan W.
Reliance of Wolbachia on high rates of host proteolysis revealed by a genome-wide RNAi screen of Drosophila cells.
Genetics 205:1473-1488(2017)

PubMed=30422992; DOI=10.1371/journal.ppat.1007445; PMCID=PMC6258568
Grobler Y., Yun C.Y., Kahler D.J., Bergman C.M., Lee H., Oliver B., Lehmann R.
Whole genome screen reveals a novel relationship between Wolbachia levels and Drosophila host translation.
PLoS Pathog. 14:E1007445-E1007445(2018)

Cross-references
Cell line databases/resources FlyBase_Cell_line; FBtc9000070
Encyclopedic resources Wikidata; Q107115517
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number5