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Cellosaurus UM-SCC-10BPT (CVCL_A5TP)

[Text version]
Cell line name UM-SCC-10BPT
Synonyms 10BPT; 10B PT
Accession CVCL_A5TP
Resource Identification Initiative To cite this cell line use: UM-SCC-10BPT (RRID:CVCL_A5TP)
Comments Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Derived from site: Metastatic; Submental lymph node; UBERON=UBERON_0016397.
Sequence variations
  • Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=16020667).
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7714 (UM-SCC-10B)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=16020667; DOI=10.1158/1535-7163.MCT-05-0081
Bauer J.A., Trask D.K., Kumar B., Los G., Castro J., Lee J.S.-J., Chen J.-Y., Wang S.-M., Bradford C.R., Carey T.E.
Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL.
Mol. Cancer Ther. 4:1096-1104(2005)

Cross-references
Encyclopedic resources Wikidata; Q107117255
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number4