ID   Wilms10T
AC   CVCL_A5SL
SY   Wilms10
DR   CLS; 300417
DR   GEO; GSM1831635
DR   GEO; GSM1831636
DR   Wikidata; Q107117465
RX   PubMed=27213811;
RX   PubMed=33379206;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; HGNC:12796; WT1; Zygosity=Homozygous; Note=Nested within a heterozygous 11p13 deletion (PubMed=27213811; PubMed=33379206).
CC   Sequence variation: Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45del (c.133_135delTCT); ClinVar=VCV000017576; Zygosity=Homozygous (PubMed=27213811; PubMed=33379206).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
ST   Source(s): CLS=300417; PubMed=33379206
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 12 (CLS=300417)
ST   D13S317: 12,13 (PubMed=33379206)
ST   D16S539: 9,10
ST   D18S51: 14,16
ST   D21S11: 29,30
ST   D3S1358: 17
ST   D5S818: 10,12
ST   D7S820: 11,12
ST   D8S1179: 10,15
ST   FGA: 22,24
ST   Penta D: 10,13
ST   Penta E: 7,10
ST   TH01: 8
ST   TPOX: 8,11
ST   vWA: 15,18
DI   NCIt; C40407; Kidney Wilms tumor
DI   ORDO; Orphanet_654; Nephroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_A5SK ! Wilms10M
SX   Female
AG   2Y
CA   Finite cell line
DT   Created: 20-05-21; Last updated: 19-12-24; Version: 7
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RX   PubMed=27213811; DOI=10.1371/journal.pone.0155561; PMCID=PMC4876997;
RA   Brandt A., Lohers K., Beier M., Leube B., de Torres C., Mora J.,
RA   Arora P., Jat P.S., Royer-Pokora B.;
RT   "Establishment of a conditionally immortalized Wilms tumor cell line
RT   with a homozygous WT1 deletion within a heterozygous 11p13 deletion
RT   and UPD limited to 11p15.";
RL   PLoS ONE 11:E0155561-E0155561(2016).
//
RX   PubMed=33379206; DOI=10.3390/cancers13010060; PMCID=PMC7801943;
RA   Royer-Pokora B., Busch M.A., Tenbusch S., Schmidt M., Beier M.,
RA   Woods A.D., Thiele H., Mora J.;
RT   "Comprehensive biology and genetics compendium of Wilms tumor cell
RT   lines with different WT1 mutations.";
RL   Cancers (Basel) 13:60.1-60.21(2021).
//