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Cellosaurus Wilms10M (CVCL_A5SK)

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Cell line name Wilms10M
Accession CVCL_A5SK
Resource Identification Initiative To cite this cell line use: Wilms10M (RRID:CVCL_A5SK)
Comments Population: Caucasian.
Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Gene deletion; HGNC; HGNC:12796; WT1; Zygosity=Homozygous; Note=Nested within a heterozygous 11p13 deletion (PubMed=33379206).
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45del (c.133_135delTCT); ClinVar=VCV000017576; Zygosity=Homozygous (PubMed=33379206).
Disease Kidney Wilms tumor (NCIt: C40407)
Nephroblastoma (ORDO: Orphanet_654)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A5SL ! Wilms10T
Sex of cell Female
Age at sampling 2Y
Category Finite cell line
STR profile Source(s): PubMed=33379206

Markers:
AmelogeninX
CSF1PO11,12
D3S135817
D5S81810,12
D7S82011,12
D8S117910,15
D13S31712
D16S5399,10
D18S5114,16
D21S1129,30
FGA22,24
Penta D10,13
Penta E7,10
TH018
TPOX8,11
vWA15,18

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Publications

PubMed=33379206; DOI=10.3390/cancers13010060; PMCID=PMC7801943
Brigitte Royer-Pokora, Maike Anna Busch, Sarah Tenbusch, Mathias Schmidt, Manfred Beier, Andrew D. Woods, Holger Thiele, Jaume Mora;
Comprehensive biology and genetics compendium of Wilms tumor cell lines with different WT1 mutations.
Cancers (Basel) 13:60.1-60.21(2021)

Cross-references
Cell line collections (Providers) CLS; 300418
Encyclopedic resources Wikidata; Q107117464
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number6