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Cellosaurus Wilms10M (CVCL_A5SK)

[Text version]
Cell line name Wilms10M
Accession CVCL_A5SK
Resource Identification Initiative To cite this cell line use: Wilms10M (RRID:CVCL_A5SK)
Comments Population: Caucasian.
Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Gene deletion; HGNC; HGNC:12796; WT1; Zygosity=Homozygous; Note=Nested within a heterozygous 11p13 deletion (PubMed=33379206).
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45del (c.133_135delTCT); ClinVar=VCV000017576; Zygosity=Homozygous (PubMed=33379206).
Disease Kidney Wilms tumor (NCIt: C40407)
Nephroblastoma (ORDO: Orphanet_654)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A5SL ! Wilms10T
Sex of cell Female
Age at sampling 2Y
Category Finite cell line
STR profile Source(s): PubMed=33379206

Markers:
AmelogeninX
CSF1PO11,12
D3S135817
D5S81810,12
D7S82011,12
D8S117910,15
D13S31712
D16S5399,10
D18S5114,16
D21S1129,30
FGA22,24
Penta D10,13
Penta E7,10
TH018
TPOX8,11
vWA15,18

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Publications

PubMed=33379206; DOI=10.3390/cancers13010060; PMCID=PMC7801943
Royer-Pokora B., Busch M.A., Tenbusch S., Schmidt M., Beier M., Woods A.D., Thiele H., Mora J.
Comprehensive biology and genetics compendium of Wilms tumor cell lines with different WT1 mutations.
Cancers (Basel) 13:60.1-60.21(2021)

Cross-references
Cell line collections (Providers) CLS; 300418
Encyclopedic resources Wikidata; Q107117464
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number6