Cellosaurus cell line Wilms6 (CVCL

Cellosaurus Wilms6 (CVCL_A5SI)

[Text version]

Cell line name

Wilms6

Accession

CVCL_A5SI

Resource Identification Initiative

To cite this cell line use: Wilms6 (RRID:CVCL_A5SI)

Comments

Population: Caucasian.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.

Sequence variations

Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45del (c.133_135delTCT); ClinVar=VCV000017576; Zygosity=Homozygous (PubMed=33379206).
Mutation; HGNC; HGNC:12796; WT1; Simple; p.Arg390Ter (c.1168C>T) (p.Arg463Ter, c.1387C>T); ClinVar=VCV000003494; Zygosity=Homozygous (PubMed=33379206).

Disease

Kidney Wilms tumor (NCIt: C40407)
Nephroblastoma (ORDO: Orphanet_654)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_A5SQ (imWilms6)

Sex of cell

Male

Age at sampling

1Y3M

Category

Finite cell line

STR profile

Source(s): CLS=300415; PubMed=33379206

Markers:

Amelogenin	X,Y
CSF1PO	11,12
D3S1358	15,16
D5S818	8,9
D7S820	8,11
D8S1179	11,13
D13S317	8,11
D16S539	9,11
D18S51	12,16
D21S11	28,30
FGA	22,23
Penta D	11
Penta E	8,13
TH01	9
TPOX	11
vWA	16,18

Publications

PubMed=33379206; DOI=10.3390/cancers13010060; PMCID=PMC7801943
Royer-Pokora B., Busch M.A., Tenbusch S., Schmidt M., Beier M., Woods A.D., Thiele H., Mora J.
Comprehensive biology and genetics compendium of Wilms tumor cell lines with different WT1 mutations.
Cancers (Basel) 13:60.1-60.21(2021)

Cross-references

Cell line collections (Providers)

CLS; 300415

Encyclopedic resources

Wikidata; Q107117473

Entry history

Entry creation

20-May-2021

Last entry update

19-Dec-2024

Version number