Cellosaurus cell line CD#68 iPSC (CVCL

Cellosaurus CD#68 iPSC (CVCL_A5RM)

[Text version]

Cell line name

CD#68 iPSC

Accession

CVCL_A5RM

Resource Identification Initiative

To cite this cell line use: CD#68 iPSC (RRID:CVCL_A5RM)

Comments

Population: Jewish.
Cell type: Fibroblast; CL=CL_0000057.

Sequence variations

Mutation; HGNC; HGNC:756; ASPA; Simple; p.Glu285Ala (c.854A>C); ClinVar=VCV000002605; Zygosity=Homozygous (PubMed=33304759).

Disease

Canavan disease (NCIt: C84611)
Canavan disease (ORDO: Orphanet_141)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0P45 (GM04268)
Children:

CVCL_A5RU (CD#68T-13 iPSC)

Sex of cell

Male

Age at sampling

Category

Induced pluripotent stem cell

STR profile

Source(s): PubMed=33304759

Markers:

Amelogenin	X,Y
CSF1PO	11
D5S818	10,12
D7S820	9,12
D13S317	11,12
D16S539	10,13
D21S11	29,31.2
TH01	9,9.3
TPOX	9,11
vWA	17,18

Publications

PubMed=33304759; DOI=10.1002/advs.202002155; PMCID=PMC7709977
Feng L.-Z., Chao J.-F., Tian E., Li L., Ye P., Zhang M., Chen X.-W., Cui Q., Sun G.-H., Zhou T., Felix G., Qin Y., Li W.-D., Meza E.D., Klein J., Ghoda L.Y., Hu W.-D., Luo Y.-L., Dang W., Hsu D., Gold J.D., Goldman S.A., Matalon R.K., Shi Y.-H.
Cell-based therapy for Canavan disease using human iPSC-derived NPCs and OPCs.
Adv. Sci. (Weinh.) 7:2002155.1-2002155.19(2020)

Cross-references

Encyclopedic resources

Wikidata; Q107114634

Entry history

Entry creation

20-May-2021

Last entry update

19-Dec-2024

Version number