Cellosaurus COS-F2-130 (CVCL_A5QA)
| Cell line name | COS-F2-130 |
|---|---|
| Accession | CVCL_A5QA |
| Resource Identification Initiative | To cite this cell line use: COS-F2-130 (RRID:CVCL_A5QA) |
| Comments | Group: Non-human primate cell line. Characteristics: Useful system for studying steroidogenesis. Converts cholesterol to pregnenolone but lack downstream enzymes that catalyze other steroidogenic reactions (PubMed=11356706). Characteristics: Transfected with the F2 construct that consist of the fusion of P450scc-adrenodoxin reductase-adrenodoxin (PubMed=11356706). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:2590; CYP11A1. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3638; FDX1. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3642; FDXR. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV6-1). Derived from site: In situ; Kidney; UBERON=UBERON_0002113. |
| Species of origin | Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) (NCBI Taxonomy: 9534) |
| Hierarchy | Parent: CVCL_0223 (COS-1) |
| Sex of cell | Male |
| Age at sampling | Adult |
| Category | Transformed cell line |
| Publications | PubMed=11356706; DOI=10.1210/endo.142.6.8206 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q107114704 |
| Entry history | |
| Entry creation | 20-May-2021 |
| Last entry update | 19-Dec-2024 |
| Version number | 7 |