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Cellosaurus CHO-K1 Mev-SM (CVCL_A5KE)

[Text version]
Cell line name CHO-K1 Mev-SM
Synonyms Mev-SM
Accession CVCL_A5KE
Resource Identification Initiative To cite this cell line use: CHO-K1 Mev-SM (RRID:CVCL_A5KE)
Comments Characteristics: Repairs the deficiency in mevalonate biosynthesis of the parent cell line (PubMed=7961793).
Genetic integration: Method=Transfection/transduction; Gene=RGD; 2804; Hmgcs2.
Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_A5KD (CHO-K1 Mev-1)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=7961793; DOI=10.1016/S0021-9258(19)61932-0
Ortiz J.A., Gil-Gomez G., Casaroli-Marano R.P., Vilaro S., Hegardt F.G., Haro D.
Transfection of the ketogenic mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme A synthase cDNA into Mev-1 cells corrects their auxotrophy for mevalonate.
J. Biol. Chem. 269:28523-28526(1994)

Cross-references
Encyclopedic resources Wikidata; Q107114657
Entry history
Entry creation20-May-2021
Last entry update10-Sep-2024
Version number6