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Cellosaurus FM3A tsFT50 (CVCL_A5JY)

[Text version]
Cell line name FM3A tsFT50
Synonyms tsFT50
Accession CVCL_A5JY
Resource Identification Initiative To cite this cell line use: FM3A tsFT50 (RRID:CVCL_A5JY)
Comments Characteristics: Temperature sensitive phenotype. Cytokinesis is blocked at 39 Celsius.
Transformant: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Sequence variations
  • Mutation; MGI; MGI:1927222; Diaph3; Simple; p.Gln668Ter (c.2002C>T); Zygosity=Homozygous (PubMed=33187357).
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/He.
Hierarchy Parent: CVCL_3869 (FM3A)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=33187357; DOI=10.3390/ijms21228493; PMCID=PMC7696919
Kazama H., Kashiwaba S.-i., Ishii S., Yoshida K., Yatsuo Y., Naraoka T., Fukuoka M., Murakami Y.
Loss of DIAPH3, a formin family protein, leads to cytokinetic failure only under high temperature conditions in mouse FM3A cells.
Int. J. Mol. Sci. 21:8493.1-8493.17(2020)

Cross-references
Encyclopedic resources Wikidata; Q107115053
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number4