ID   RD-SCARB2
AC   CVCL_A5IA
SY   RDS
DR   cancercelllines; CVCL_A5IA
DR   Wikidata; Q107116731
RX   PubMed=23919614;
CC   Population: Caucasian.
CC   Virology: Highly susceptible to infection by enterovirus type 71 (EV71) and coxsackievirus A group type 16 (CA16) (PubMed=23919614).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000373003; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 1665; SCARB2.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Pelvis, muscle; UBERON=UBERON_0001325.
DI   NCIt; C8971; Embryonal rhabdomyosarcoma
DI   ORDO; Orphanet_99757; Embryonal rhabdomyosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1649 ! RD
SX   Female
AG   7Y
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 05-10-23; Version: 8
//
RX   PubMed=23919614; DOI=10.1186/1743-422X-10-250;
RA   Li X.-J., Fan P.-H., Jin J., Su W.-H., An D., Xu L., Sun S.-Y.,
RA   Zhang Y., Meng X.-Y., Gao F., Kong W., Jiang C.-L.;
RT   "Establishment of cell lines with increased susceptibility to
RT   EV71/CA16 by stable overexpression of SCARB2.";
RL   Virol. J. 10:250.1-250.11(2013).
//