ID   NS46C
AC   CVCL_A5EK
SY   LC-1; LC1
DR   Wikidata; Q107116581
RX   PubMed=16086633;
RX   PubMed=21454627;
WW   https://biokryo.airliquide.com/sites/biokryo/files/2022-07/animal-stem-cells-catalogue-isenet.pdf
CC   Characteristics: Expresses eGFP under the control of the Sox-1 promoter.
CC   Doubling time: ~24 hours (PubMed=16086633).
CC   Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Neural stem cell; CL=CL_0000047.
CC   Breed/subspecies: 129P2/Ola.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_Y482 ! 46C
SX   Male
AG   Blastocyst stage
CA   Somatic stem cell
DT   Created: 20-05-21; Last updated: 10-09-24; Version: 7
//
RX   PubMed=16086633; DOI=10.1371/journal.pbio.0030283; PMCID=PMC1184591;
RA   Conti L., Pollard S.M., Gorba T., Reitano E., Toselli M., Biella G.,
RA   Sun Y.-R., Sanzone S., Ying Q.-L., Cattaneo E., Smith A.G.;
RT   "Niche-independent symmetrical self-renewal of a mammalian tissue stem
RT   cell.";
RL   PLoS Biol. 3:e283.1594-e283.1606(2005).
//
RX   PubMed=21454627; DOI=10.1074/jbc.M110.210740; PMCID=PMC3099688;
RA   Cardano M., Diaferia G.R., Cattaneo M., Dessi S.S., Long Q.-M.,
RA   Conti L., DeBlasio P., Cattaneo E., Biunno I.;
RT   "mSEL-1L (suppressor/enhancer Lin12-like) protein levels influence
RT   murine neural stem cell self-renewal and lineage commitment.";
RL   J. Biol. Chem. 286:18708-18719(2011).
//