Cellosaurus logo
expasy logo

Cellosaurus HEK293T-CAF40-null (CVCL_A5EE)

[Text version]
Cell line name HEK293T-CAF40-null
Synonyms CAF40-null HEK293T
Accession CVCL_A5EE
Resource Identification Initiative To cite this cell line use: HEK293T-CAF40-null (RRID:CVCL_A5EE)
Comments Doubling time: ~30-40 hours (DSMZ=ACC-872).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:10445; CNOT9.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
STR profile Source(s): DSMZ=ACC-872

Markers:
AmelogeninX
CSF1PO11,12
D2S133819
D3S135815,17
D5S8188,9
D7S82011
D8S117911,12,14
D13S31712,14
D16S5399,13
D18S5117,18
D19S43317,18,19
D21S1128,30.2
FGA23
Penta D9,10
Penta E7,15
TH017,9.3
TPOX11
vWA16,18,20

Run an STR similarity search on this cell line
Publications

PubMed=29255063; DOI=10.1261/rna.064584.117; PMCID=PMC5824357
Sgromo A., Raisch T., Backhaus C., Keskeny C., Alva V., Weichenrieder O., Izaurralde E.
Drosophila Bag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets.
RNA 24:381-395(2018)

Cross-references
Cell line collections (Providers) DSMZ; ACC-872
Cell line databases/resources DSMZCellDive; ACC-872
Encyclopedic resources Wikidata; Q107115306
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number9