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Cellosaurus Hep-G2 VA-28 (CVCL_A5CR)

[Text version]
Cell line name Hep-G2 VA-28
Synonyms VA-28
Accession CVCL_A5CR
Resource Identification Initiative To cite this cell line use: Hep-G2 VA-28 (RRID:CVCL_A5CR)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:87921; Adh1.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=11981770; DOI=10.1053/jhep.2002.32668
Clemens D.L., Forman A., Jerrells T.R., Sorrell M.F., Tuma D.J.
Relationship between acetaldehyde levels and cell survival in ethanol-metabolizing hepatoma cells.
Hepatology 35:1196-1204(2002)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A5CR
Encyclopedic resources Wikidata; Q107115327
Entry history
Entry creation20-May-2021
Last entry update10-Sep-2024
Version number6