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Cellosaurus Bm7brm (CVCL_A5BT)

[Text version]
Cell line name Bm7brm
Accession CVCL_A5BT
Resource Identification Initiative To cite this cell line use: Bm7brm (RRID:CVCL_A5BT)
Comments Population: Chinese; Taiwan.
Characteristics: Metastatic to brain. Established from intracardiac injection of parent cell in SCID mice and cultured from brain tissue.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A5BS (Bm7)
Sex of cell Male
Age at sampling 64Y
Category Cancer cell line
Publications

PubMed=25060522; DOI=10.1158/0008-5472.CAN-13-2995
Lin C.-Y., Chen H.-J., Huang C.-C., Lai L.-C., Lu T.-P., Tseng G.-C., Kuo T.-T., Kuok Q.-Y., Hsu J.L., Sung S.-Y., Hung M.-C., Sher Y.-P.
ADAM9 promotes lung cancer metastases to brain by a plasminogen activator-based pathway.
Cancer Res. 74:5229-5243(2014)

Cross-references
Anatomy/cell type resources BTO; BTO_0006478
Encyclopedic resources Wikidata; Q107113471
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number6