Cellosaurus NCI-H249 (CVCL_A537)
Cell line name | NCI-H249 | ||||||||||||||||||
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Synonyms | H249; H-249; NCIH249 | ||||||||||||||||||
Accession | CVCL_A537 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: NCI-H249 (RRID:CVCL_A537) | ||||||||||||||||||
Comments | Problematic cell line: Contaminated. Shown to be a NCI-H69 derivative (PubMed=20143388). Originally thought to originate from the bone marrow of a male patient with small cell lung cancer. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00334. Population: Caucasian. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. | ||||||||||||||||||
Sequence variations |
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Disease | Lung small cell carcinoma (NCIt: C4917) Small cell lung cancer (ORDO: Orphanet_70573) | ||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
Hierarchy | Parent: CVCL_1579 (NCI-H69) | ||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||
Age at sampling | 55Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): ATCC=CRL-5827 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Web pages | https://www.atcc.org/en/support/technical-support/faqs/nci-h249-atcc-crl-5827 https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx | ||||||||||||||||||
Publications | PubMed=6148444; DOI=10.1093/jnci/73.4.801 PubMed=6713399 PubMed=2985257 PubMed=3335022 PubMed=1845952; DOI=10.1002/1097-0142(19910201)67:3<619::AID-CNCR2820670317>3.0.CO;2-Y PubMed=1320893; DOI=10.1159/000163712 PubMed=8806092; DOI=10.1002/jcb.240630505 PubMed=8806103; DOI=10.1002/jcb.240630516 PubMed=11030152; DOI=10.1038/sj.onc.1203815 PubMed=20143388; DOI=10.1002/ijc.25242 PubMed=31803961; DOI=10.1002/jcb.29564; PMCID=PMC7496084 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections (Providers) | ATCC; CRL-5827 - Discontinued
KCLB; 90249 - Discontinued | ||||||||||||||||||
Cell line databases/resources | cancercelllines; CVCL_A537 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03151645
BioSample; SAMN03151860 BioSample; SAMN03471746 | ||||||||||||||||||
Encyclopedic resources | Wikidata; Q54907977 | ||||||||||||||||||
Gene expression databases | GEO; GSM845545
GEO; GSM844646 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 755460
Cosmic; 877204 Cosmic; 980931 Cosmic; 1006529 Cosmic; 1021857 Cosmic; 1032397 Cosmic; 2125249 IARC_TP53; 21566 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 06-Jun-2012 | ||||||||||||||||||
Last entry update | 19-Dec-2024 | ||||||||||||||||||
Version number | 34 |