Cellosaurus cell line Mt2-fibro (CVCL_A4RJ)

Cellosaurus Mt2-fibro (CVCL_A4RJ)

Cell line name

Mt2-fibro

Accession

CVCL_A4RJ

Resource Identification Initiative

To cite this cell line use: Mt2-fibro (RRID:CVCL_A4RJ)

Comments

Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.

Sequence variations

Mutation; HGNC; HGNC:7490; MT-TL1; Simple; m.3243A>G; ClinVar=VCV000009589; Zygosity=Heteroplasmic (PubMed=22396012).

Disease

Mitochondrial diabetes (NCIt: C131859)
Maternally-inherited diabetes and deafness (ORDO: Orphanet_225)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_A4RU (Mt2-1)	CVCL_A4SD (Mt2-10)	CVCL_A4RV (Mt2-2)
CVCL_A4RW (Mt2-3)	CVCL_A4RX (Mt2-4)	CVCL_A4RY (Mt2-5)
CVCL_A4RZ (Mt2-6)	CVCL_A4SA (Mt2-7)	CVCL_A4SB (Mt2-8)
CVCL_A4SC (Mt2-9)

Sex of cell

Female

Age at sampling

46Y

Category

Finite cell line

Publications

PubMed=22396012; DOI=10.1007/s00125-012-2508-2
Fujikura J., Nakao K., Sone M., Noguchi M., Mori E., Naito M., Taura D., Harada-Shiba M., Kishimoto I., Watanabe A., Asaka I., Hosoda K., Nakao K.
Induced pluripotent stem cells generated from diabetic patients with mitochondrial DNA A3243G mutation.
Diabetologia 55:1689-1698(2012)

Cross-references

Encyclopedic resources

Wikidata; Q105510215

Entry history

Entry creation

12-Jan-2021

Last entry update

19-Dec-2024

Version number

6