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Cellosaurus Abcc8-A2 (CVCL_A4GW)

[Text version]
Cell line name Abcc8-A2
Accession CVCL_A4GW
Resource Identification Initiative To cite this cell line use: Abcc8-A2 (RRID:CVCL_A4GW)
Comments From: Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences; Guangzhou; China.
Knockout cell: Method=CRISPR/Cas9; HGNC; 59; ABCC8 (Note=1 of 2 alleles).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Disease Persistent hyperinsulinemic hypoglycemia of infancy (NCIt: C122923)
Autosomal dominant hyperinsulinism due to SUR1 deficiency (ORDO: Orphanet_276575)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9771 (WA01)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=27934605; DOI=10.1016/j.scr.2016.11.014
Guo D.-S., Liu H.-K., Gao G., Ruzi A., Wang K.-P., Wu H., Lai K.-Y., Liu Y.-L., Yang F., Lai L.-X., Li Y.-X.
Generation of an Abcc8 heterozygous mutation human embryonic stem cell line using CRISPR/Cas9.
Stem Cell Res. 17:670-672(2016)

Cross-references
Encyclopedic resources Wikidata; Q105506049
Entry history
Entry creation12-Jan-2021
Last entry update30-Jan-2024
Version number6