Cellosaurus logo
expasy logo

Cellosaurus Abcc8-A4 (CVCL_A4GR)

[Text version]
Cell line name Abcc8-A4
Accession CVCL_A4GR
Resource Identification Initiative To cite this cell line use: Abcc8-A4 (RRID:CVCL_A4GR)
Comments From: Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences; Guangzhou; China.
Knockout cell: Method=CRISPR/Cas9; HGNC; 59; ABCC8.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Disease Persistent hyperinsulinemic hypoglycemia of infancy (NCIt: C122923)
Autosomal dominant hyperinsulinism due to SUR1 deficiency (ORDO: Orphanet_276575)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9771 (WA01)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=27934599; DOI=10.1016/j.scr.2016.11.011
Guo D.-S., Liu H.-K., Gao G., Ruzi A., Wang K.-P., Wu H., Lai K.-Y., Liu Y.-L., Yang F., Lai L.-X., Li Y.-X.
Generation of an Abcc8 homozygous mutation human embryonic stem cell line using CRISPR/Cas9.
Stem Cell Res. 17:640-642(2016)

Cross-references
Encyclopedic resources Wikidata; Q105506051
Entry history
Entry creation12-Jan-2021
Last entry update29-Jun-2023
Version number5