ID   FaDu-Luc2
AC   CVCL_A4CG
DR   ATCC; HTB-43-LUC2
DR   cancercelllines; CVCL_A4CG
DR   Wikidata; Q105506862
CC   Population: Indian.
CC   Characteristics: Stably expresses firefly luciferase under the control of the human EF1a promoter (ATCC=HTB-43-LUC2).
CC   Doubling time: ~30 hours (ATCC=HTB-43-LUC2).
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; c.151-1G>T; ClinVar=VCV000422058; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 3595; FAT1; Simple; p.Lys3277Asnfs*4 (c.9828delG) (p.Gly3276fs); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Heterozygous; Note=Splice acceptor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Leu (c.743G>T); ClinVar=VCV000230253; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: UniProtKB; P08659; Firefly luciferase (with optimized codon usage for mammalian expression).
CC   Transfected with: UniProtKB; P33967; B.cereus Bsr.
CC   Derived from site: In situ; Pharynx, hypopharynx; UBERON=UBERON_0001051.
ST   Source(s): ATCC=HTB-43-LUC2
ST   Amelogenin: Not_detected
ST   CSF1PO: 12
ST   D13S317: 8,9
ST   D16S539: 11
ST   D5S818: 12
ST   D7S820: 11,12
ST   TH01: 8
ST   TPOX: 11
ST   vWA: 15,17
DI   NCIt; C4043; Hypopharyngeal squamous cell carcinoma
DI   ORDO; Orphanet_494547; Squamous cell carcinoma of the hypopharynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1218 ! FaDu
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 12-01-21; Last updated: 02-05-24; Version: 7
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