Cellosaurus MCF 10A Ecadherin EmGFP (CVCL_A4BW)
| Cell line name | MCF 10A Ecadherin EmGFP | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Synonyms | MCF 10A ECAD-EmGFP | ||||||||||||||||||
| Accession | CVCL_A4BW | ||||||||||||||||||
| Resource Identification Initiative | To cite this cell line use: MCF 10A Ecadherin EmGFP (RRID:CVCL_A4BW) | ||||||||||||||||||
| Comments | Characteristics: Using CRISPR/Cas9 CDH1 has been tagged in one allele at the C-terminus with EmGFP. Allows to monitor the epithelial-to-mesenchymal transition (EMT) status of cells in vitro by monitoring EmGFP expression. Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; GLAD6; Emerald (Note=EmGFP, green fluorescent protein derived from GFP). Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367. | ||||||||||||||||||
| Sequence variations | |||||||||||||||||||
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
| Hierarchy | Parent: CVCL_0598 (MCF-10A) | ||||||||||||||||||
| Sex of cell | Female | ||||||||||||||||||
| Age at sampling | 36Y | ||||||||||||||||||
| Category | Spontaneously immortalized cell line | ||||||||||||||||||
| STR profile | Source(s): ATCC=CRL-10317EMT Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
| Cross-references | |||||||||||||||||||
| Cell line collections (Providers) | ATCC; CRL-10317EMT | ||||||||||||||||||
| Encyclopedic resources | Wikidata; Q105510065 | ||||||||||||||||||
| Entry history | |||||||||||||||||||
| Entry creation | 12-Jan-2021 | ||||||||||||||||||
| Last entry update | 19-Dec-2024 | ||||||||||||||||||
| Version number | 10 | ||||||||||||||||||